Last reviewed · How we verify
Systemic AL amyloidosis
Approved treatments
- Wydase · Baxter
Hyaluronidase increases tissue permeability by breaking down hyaluronic acid, promoting the diffusion and absorption of injected fluids. - Decadron · Generic (originally Merck)
- Cyclophosphamid · Zhejiang University
- Velcade · University of Arkansas
- Velcade · Shilpa
Reversible inhibitor of 26S proteasome chymotrypsin-like activity preventing ubiquitinated protein degradation. - Cytoxan (Lyophilized) · Baxter
Cyclophosphamide cross-links tumor cell DNA and interferes with malignant cell growth through active alkylating metabolites. - Darzalex · Johnson & Johnson
Daratumumab binds CD38 on tumor cells, inducing apoptosis and immune-mediated lysis via CDC, ADCC, and ADCP. - Cytoxan (Lyophilized) · Baxter
Cytoxan works by interfering with the DNA replication process in rapidly dividing cancer cells. - Darzalex · Shanghai Henlius Biotech
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Systemic AL amyloidosis patent landscape — cliff calendar, originator estates, attackable patents
- Systemic AL amyloidosis treatment landscape brief
- Systemic AL amyloidosis treatment updates RSS
Frequently asked questions about Systemic AL amyloidosis
What drugs treat Systemic AL amyloidosis?
Tracked treatments include Wydase, Decadron, Cyclophosphamid, Velcade, Cytoxan (Lyophilized), Darzalex.
What is the treatment for Systemic AL amyloidosis?
Standard treatment for Systemic AL amyloidosis includes Wydase, Decadron, Cyclophosphamid, Velcade, Cytoxan (Lyophilized). See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Systemic AL amyloidosis patent cliff · Systemic AL amyloidosis CI report
- Treatment: Wydase · Baxter
- Treatment: Decadron · Generic (originally Merck)
- Treatment: Cyclophosphamid · Zhejiang University
- Treatment: Velcade · University of Arkansas
- Treatment: Velcade · Shilpa
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing