Severe Pain With Opioid Tolerance — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for severe pain with opioid tolerance. 14 active patents protecting 1 drugs from 1+ originators. First major cliff: 2032. Daily refresh.

1
Approved drugs
14
Active US patents
46/100
Avg vulnerability
Annual revenue covered

Originators in Severe Pain With Opioid Tolerance

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Fresenius Kabi 14 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating severe pain with opioid tolerance. Each bar = one year. Y-axis scaled to peak year (7 patents).

7
32
7
34

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Dilaudid-Hp
Hydromorphone Hydrochloride
Fresenius Kabi 14 46 2032-04-23

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
9731082 Dilaudid-Hp formulation 56 2032-04-23
9248229 Dilaudid-Hp formulation 50 2034-03-12
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12
9248229 Dilaudid-Hp formulation 42 2034-03-12
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23
9731082 Dilaudid-Hp formulation 48 2032-04-23

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