Prevention Of Post Operative Nausea And Vomiting — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for prevention of post operative nausea and vomiting. 42 active patents protecting 3 drugs from 3+ originators. First major cliff: 2029. Daily refresh.

3
Approved drugs
42
Active US patents
62/100
Avg vulnerability
—
Annual revenue covered

Originators in Prevention Of Post Operative Nausea And Vomiting

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Merck & Co. 31 patents Hikma 7 patents GSK (originally Glaxo) 4 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating prevention of post operative nausea and vomiting. Each bar = one year. Y-axis scaled to peak year (27 patents).

4
27
7
29
3
30
27
35
1
38

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Emend
APREPITANT
 Merck & Co. 31 60 — 2027-09-26
Reglan
Metoclopramide Hydrochloride
 Hikma 7 75 — 2029-12-22
Zofran
ondansetron
 GSK (originally Glaxo) 4 51 — 2029-11-23

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
12194009 Reglan method of use 81 2029-12-22
12194008 Reglan method of use 81 2029-12-22
8258132 Emend method of use 80 2027-09-26
8258132 Emend method of use 80 2027-09-26
8258132 Emend method of use 80 2027-09-26
11813231 Reglan method of use 76 2029-12-22
11628150 Reglan method of use 76 2029-12-22
8258132 Emend method of use 75 2027-09-26
11878074 Emend method of use 75 2035-09-18
12377064 Reglan method of use 75 2038-11-17

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
9974793 Emend formulation 42 2035-09-18
9974742 Emend formulation 42 2035-09-18
10500208 Emend formulation 42 2035-09-18
11173118 Emend formulation 42 2035-09-18
9095577 Zofran formulation 48 2030-07-13
9095577 Zofran formulation 48 2030-07-13
9974742 Emend formulation 50 2035-09-18
9974793 Emend formulation 50 2035-09-18
11173118 Emend formulation 50 2035-09-18
11744800 Emend formulation 50 2035-09-18

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