Preoperative Anxiety — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for preoperative anxiety. 27 active patents protecting 2 drugs from 1+ originators. First major cliff: 2028. Daily refresh.

2
Approved drugs
27
Active US patents
64/100
Avg vulnerability
—
Annual revenue covered

Originators in Preoperative Anxiety

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Generic (originally Roche) 27 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating preoperative anxiety. Each bar = one year. Y-axis scaled to peak year (15 patents).

4
28
15
29
6
32
2
38

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Valium
diazepam
 Generic (originally Roche) 21 67 — 2029-03-27
Versed
midazolam
 Generic (originally Roche) 6 61 — 2028-01-18

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8217033 Versed method of use 75 2028-01-18
9289432 Versed method of use 75 2028-01-18
9687495 Versed method of use 75 2028-01-18
12337061 Valium method of use 75 2032-06-13
12337061 Valium method of use 75 2032-06-13
12337061 Valium method of use 75 2032-06-13
12324852 Valium method of use 75 2032-10-16
12324852 Valium method of use 75 2032-10-16
12324852 Valium method of use 75 2032-10-16
12268664 Valium formulation 68 2029-03-27

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
10966990 Versed formulation 42 2038-06-20
10966990 Versed formulation 42 2038-06-20
8895546 Valium formulation 55 2029-03-27
8895546 Valium formulation 55 2029-03-27
8895546 Valium formulation 55 2029-03-27
8809322 Versed formulation 55 2028-01-18
11793786 Valium formulation 63 2029-03-27
11793786 Valium formulation 63 2029-03-27
11793786 Valium formulation 63 2029-03-27
11241414 Valium formulation 63 2029-03-27

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