Last reviewed 2026-04-19 · How we verify

Polycythemia Vera

Approved treatments

• Valchlor · Recordati
  Valchlor works by attaching an alkyl group to the DNA of cancer cells, interfering with their ability to replicate and ultimately leading to cell death.
• Besremi · Pharma Essentia Corporation
  Besremi works by binding to the interferon alpha/beta receptor, triggering a signaling cascade that reduces red blood cell production.
• Uramustin
• Phosphotope · Mallinckrodt
• Ropeginterferon · St. Olavs Hospital
• Jakafi · Incyte Corp

Pipeline

• HYDROXYUREA — Phase 3

Competitive intelligence

For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:

• Polycythemia Vera treatment landscape brief
• Polycythemia Vera treatment updates RSS