Peptic Reflux Disease — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for peptic reflux disease. 15 active patents protecting 2 drugs from 2+ originators. First major cliff: 2036. Daily refresh.

2
Approved drugs
15
Active US patents
55/100
Avg vulnerability
$1.0B
Annual revenue covered

Originators in Peptic Reflux Disease

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

AstraZeneca (originally Astra AB) 10 patents Generic (originally Yamanouchi/Merck) 5 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating peptic reflux disease. Each bar = one year. Y-axis scaled to peak year (7 patents).

5
26
2
36
7
39
1
40

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Prilosec
omeprazole
 AstraZeneca (originally Astra AB) 10 37 $1.0B 2036-12-08
Pepcid
famotidine
 Generic (originally Yamanouchi/Merck) 5 73 — 2026-07-18

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8067451 Pepcid method of use 85 2026-07-18
8501228 Pepcid method of use 85 2026-07-18
8318202 Pepcid formulation 65 2026-07-18
8449910 Pepcid formulation 65 2026-07-18
8309127 Pepcid formulation 65 2026-07-18
11911473 Prilosec method of use 58 2039-07-16
11771686 Prilosec method of use 53 2040-03-01
12329752 Prilosec formulation 38 2039-07-16
12440566 Prilosec formulation 38 2039-07-16
12042539 Prilosec formulation 38 2039-07-16

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
10835488 Prilosec formulation 25 2036-12-08
10076494 Prilosec formulation 25 2036-12-08
10751333 Prilosec formulation 33 2039-07-16
11103492 Prilosec formulation 33 2039-07-16
11633478 Prilosec formulation 33 2039-07-16
12329752 Prilosec formulation 38 2039-07-16
12440566 Prilosec formulation 38 2039-07-16
12042539 Prilosec formulation 38 2039-07-16
11771686 Prilosec method of use 53 2040-03-01
11911473 Prilosec method of use 58 2039-07-16

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