Pain In Patients For Whom Alternative Treatment Options Are Ineffective — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for pain in patients for whom alternative treatment options are ineffective. 55 active patents protecting 1 drugs from 1+ originators. First major cliff: 2026. Daily refresh.

1
Approved drugs
55
Active US patents
61/100
Avg vulnerability
—
Annual revenue covered

Originators in Pain In Patients For Whom Alternative Treatment Options Are Ineffective

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Pfizer Inc. 55 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating pain in patients for whom alternative treatment options are ineffective. Each bar = one year. Y-axis scaled to peak year (16 patents).

4
26
6
27
6
28
4
29
16
31
5
32
9
34
2
35
1
39
1
41

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Naloxone Hydrochloride Pfizer Inc. 55 61 — 2026-06-25

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
12458591 Naloxone Hydrochloride method of use 81 2032-05-11
10322239 Naloxone Hydrochloride method of use 76 2031-02-28
9474869 Naloxone Hydrochloride method of use 76 2031-02-28
10143792 Naloxone Hydrochloride method of use 76 2031-05-24
11020343 Naloxone Hydrochloride method of use 76 2032-05-11
9724471 Naloxone Hydrochloride method of use 75 2027-05-23
9724471 Naloxone Hydrochloride method of use 75 2027-05-23
12514854 Naloxone Hydrochloride method of use 75 2041-02-05
11628139 Naloxone Hydrochloride method of use 70 2034-08-26
11617713 Naloxone Hydrochloride method of use 70 2034-08-26

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
8627816 Naloxone Hydrochloride formulation 48 2032-02-04
8939943 Naloxone Hydrochloride formulation 48 2031-02-28
8939943 Naloxone Hydrochloride formulation 48 2031-02-28
9022022 Naloxone Hydrochloride formulation 48 2031-02-28
9022022 Naloxone Hydrochloride formulation 48 2031-02-28
8021344 Naloxone Hydrochloride formulation 48 2029-11-02
11027072 Naloxone Hydrochloride formulation 50 2039-05-24
11135155 Naloxone Hydrochloride formulation 50 2034-08-26
8627816 Naloxone Hydrochloride formulation 53 2032-02-04
8021344 Naloxone Hydrochloride formulation 53 2029-11-02

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