Menopausal Flushing — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for menopausal flushing. 197 active patents protecting 6 drugs from 6+ originators. First major cliff: 2039. Daily refresh.

6
Approved drugs
197
Active US patents
57/100
Avg vulnerability
—
Annual revenue covered

Originators in Menopausal Flushing

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Pfizer 101 patents Exeltis Usa Inc 42 patents Besins Hlthcare 36 patents Fdn Consumer 12 patents Azurity 3 patents Ferring 3 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating menopausal flushing. Each bar = one year. Y-axis scaled to peak year (76 patents).

24
26
6
27
12
28
9
29
10
30
31
31
76
32
4
33
11
34
4
36
2
37
1
38
3
39
1
40

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Estrace
ESTRADIOL
 Pfizer 101 37 — 2028-07-10
Slynd
DROSPIRENONE
 Exeltis Usa Inc 42 64 — 2028-01-15
Androgel
TESTOSTERONE
 Besins Hlthcare 36 72 — 2026-10-12
Jadelle
LEVONORGESTREL
 Fdn Consumer 12 48 — 2027-02-07
Testosterone Cypionate
Testosterone Cypionate
 Azurity 3 52 — 2039-03-25
Endometrin
progesterone
 Ferring 3 66 — 2029-02-03

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8466137 Androgel method of use 85 2026-10-12
8741881 Androgel method of use 85 2026-10-12
8741881 Androgel method of use 85 2026-10-12
8466138 Androgel method of use 85 2026-10-12
8466137 Androgel method of use 85 2026-10-12
8466138 Androgel method of use 85 2026-10-12
8466137 Androgel method of use 85 2026-10-12
8741881 Androgel method of use 85 2026-10-12
8466138 Androgel method of use 85 2026-10-12
8419307 Androgel method of use 85 2027-02-26

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
12004992 Jadelle composition of matter 0 2033-10-06
11795178 Estrace composition of matter 0 2033-09-27
12325714 Estrace composition of matter 0 2033-09-27
11865179 Estrace composition of matter 0 2032-11-21
11865179 Estrace composition of matter 0 2032-11-21
8231906 Estrace composition of matter 0 2030-07-04
8231906 Estrace composition of matter 0 2030-07-04
8231906 Estrace composition of matter 0 2030-07-04
8231906 Estrace composition of matter 0 2030-07-04
8231906 Estrace composition of matter 0 2030-07-04

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