Mantle Cell Lymphoma — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for mantle cell lymphoma. 479 active patents protecting 5 drugs from 5+ originators. First major cliff: 2026. Daily refresh.

5
Approved drugs
479
Active US patents
56/100
Avg vulnerability
$12.1B
Annual revenue covered

Originators in Mantle Cell Lymphoma

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

AbbVie 448 patents Bristol-Myers Squibb 12 patents AstraZeneca 9 patents Shilpa 7 patents Pfizer 3 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating mantle cell lymphoma. Each bar = one year. Y-axis scaled to peak year (117 patents).

72
26
93
27
13
28
117
31
6
32
81
33
30
34
22
35
38
36
1
39

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Imbruvica
ibrutinib
 AbbVie 448 43 $3.2B 2026-12-28
Revlimid
lenalidomide
 Bristol-Myers Squibb 12 54 $5.8B 2027-04-27
Calquence
ACALABRUTINIB
 AstraZeneca 9 53 $3.1B 2026-11-24
Velcade
bortezomib
 Shilpa 7 62 — 2032-11-03
Torisel
temsirolimus
 Pfizer 3 66 — 2026-07-20

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8026276 Torisel other 80 2026-07-20
8741929 Revlimid method of use 80 2028-03-08
8741929 Revlimid method of use 80 2028-03-08
8741929 Revlimid method of use 80 2028-03-08
8741929 Revlimid method of use 80 2028-03-08
8741929 Revlimid method of use 80 2028-03-08
8741929 Revlimid method of use 80 2028-03-08
8703780 Imbruvica method of use 76 2026-12-28
8952015 Imbruvica method of use 76 2026-12-28
8476284 Imbruvica method of use 76 2026-12-28

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
9296753 Imbruvica composition of matter 0 2033-10-30
10125140 Imbruvica composition of matter 0 2033-06-03
10106548 Imbruvica composition of matter 0 2033-06-03
10106548 Imbruvica composition of matter 0 2033-06-03

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