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Local anesthesia
Approved treatments
- Salonpas
- Naropin · Fresenius Kabi
- Versed · Takeda Pharmaceutical Company Limited
- Chlordiazepoxide Hydrochloride · Bausch Health
- Versed · Generic (originally Roche)
- Carbocaine · Eastman Kodak
- Bupivacaine Hydrochloride And Epinephrine · Innocoll
Bupivacaine works by blocking nerve impulses to prevent pain signals from reaching the brain. - Citanest
- Goprelto
- Fentanyl (F2) · Oslo University Hospital
- Octapressin
Octapressin works by binding to the vasopressin V1a receptor, which blocks pain signals to the brain. - Ceepryn
- pethidine
- Bupivacain · Sisli Hamidiye Etfal Training and Research Hospital
- Lignocaine · University of Malaya
- Ropivacain · University Hospital, Basel, Switzerland
- Naropine · Rigshospitalet, Denmark
- Lignospan Forte · Fresenius Kabi
Lidocaine stabilizes neuronal membrane by inhibiting ionic fluxes required for impulse initiation and conduction. - Chelen
Ethyl chloride works by blocking sodium channels in nerve cells, preventing the transmission of pain signals to the brain. - Isocain · Pfizer
- BUCRICAINE
Bucricaine works by blocking sodium channels in nerve cells, preventing the transmission of pain signals. - Duragesic · Johnson & Johnson (Janssen Pharmaceutica)
Synthetic opioid 50-100x more potent than morphine that binds mu-opioid receptors, providing potent analgesia and anesthesia. - Levo-Dromoran · Bausch Health
Levorphanol binds primarily to mu-opioid receptors to produce analgesia, with no ceiling effect for pain relief. - Pethidin · Ain Shams University
- Naropeine · University Hospital, Rouen
- Remifentanyl · Kocaeli University
- MS Contin · Generic (multiple manufacturers)
The prototypical opioid agonist that binds mu-opioid receptors in the CNS, providing potent analgesia and serving as the reference standard for all opioids. - Dyclone
- Meperidine Hydrochloride Preservative Free · Pfizer
Meperidine Hydrochloride Preservative Free works by binding to opioid receptors in the brain, altering the perception of and response to pain. - Duramorph Pf · Pfizer
Duramorph Pf works by binding to opioid receptors in the brain and spinal cord, mimicking the natural pain-relieving chemicals in the body. - Opana Er · Endo
- Nesacaine-Mpf · Fresenius Kabi
- Benzododecinium
- Norcaine
- Chirocain · Purdue Pharma Lp
- Amobarbitone
- Nembutal Sodium · Oak Pharms
- Ketalar · Ph Health
Ketamine works by blocking the action of glutamate at the NMDA receptor, which is involved in pain perception and memory formation. - Brevital Sodium · Ph Health
- Tetracaine Hydrochloride · Alcon Labs
Tetracaine Hydrochloride works by blocking sodium channels in nerve cells to prevent pain signals from being transmitted. - Chlorprocaine · Hadassah Medical Organization
- Carbocaine · Nantes University Hospital
- Lidocain · Bayer
- Methohexitone · St Patrick's Hospital, Ireland
- xylocain · Saint-Joseph University
- Bupivacaine Hydrochloride · Pfizer
Bupivacaine blocks nerve impulse generation and conduction by increasing electrical excitation threshold and slowing action potential rise.
Clinical guidelines
- FDA label — 1L
Lidocaine is indicated for local anesthesia. - FDA label — 1L
Lidocaine is indicated for local anesthesia.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Local anesthesia patent landscape — cliff calendar, originator estates, attackable patents
- Local anesthesia treatment landscape brief
- Local anesthesia treatment updates RSS
Frequently asked questions about Local anesthesia
What drugs treat Local anesthesia?
Tracked treatments include Salonpas, Naropin, Versed, Chlordiazepoxide Hydrochloride, Carbocaine, Bupivacaine Hydrochloride And Epinephrine, Citanest, Goprelto.
What is the treatment for Local anesthesia?
Standard treatment for Local anesthesia includes Salonpas, Naropin, Versed, Chlordiazepoxide Hydrochloride, Carbocaine. See the treatment landscape page for first-line, second-line and salvage options.
What are the treatment guidelines for Local anesthesia?
FDA label publishes guidelines for Local anesthesia. 2 guideline references tracked.
Related
- Treatment landscape: Local anesthesia patent cliff · Local anesthesia CI report
- Treatment: Salonpas
- Treatment: Naropin · Fresenius Kabi
- Treatment: Versed · Takeda Pharmaceutical Company Limited
- Treatment: Chlordiazepoxide Hydrochloride · Bausch Health
- Treatment: Versed · Generic (originally Roche)
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing