Last reviewed 2026-04-19 · How we verify

Irritable bowel syndrome characterized by constipation

5 treatments

Approved treatments

Ibsrela · Ardelyx Inc
Ibsrela works by inhibiting the sodium/hydrogen exchanger 3, a protein that regulates the balance of sodium and hydrogen ions in the gut.
Linzess · AbbVie
Linzess works by activating the heat-stable enterotoxin receptor to increase fluid secretion in the intestines.
Linzess · TriHealth Inc.
Amitiza · Sucampo Pharma Llc
Amitiza works by activating chloride channels in the intestines, increasing fluid secretion and promoting bowel movements.
Zelnorm

Competitive intelligence

For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:

Irritable bowel syndrome characterized by constipation patent landscape — cliff calendar, originator estates, attackable patents
Irritable bowel syndrome characterized by constipation treatment landscape brief
Irritable bowel syndrome characterized by constipation treatment updates RSS

Frequently asked questions about Irritable bowel syndrome characterized by constipation

What drugs treat Irritable bowel syndrome characterized by constipation?

Tracked treatments include Ibsrela, Linzess, Amitiza, Zelnorm.

What is the treatment for Irritable bowel syndrome characterized by constipation?

Standard treatment for Irritable bowel syndrome characterized by constipation includes Ibsrela, Linzess, Amitiza, Zelnorm. See the treatment landscape page for first-line, second-line and salvage options.

Treatment landscape: Irritable bowel syndrome characterized by constipation patent cliff · Irritable bowel syndrome characterized by constipation CI report
Treatment: Ibsrela · Ardelyx Inc
Treatment: Linzess · AbbVie
Treatment: Linzess · TriHealth Inc.
Treatment: Amitiza · Sucampo Pharma Llc
Treatment: Zelnorm
All diseases: Browse the disease index · Disease landscape hub

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing