Edema — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for edema. 17 active patents protecting 4 drugs from 1+ originators. First major cliff: 2034. Daily refresh.

4
Approved drugs
17
Active US patents
65/100
Avg vulnerability
—
Annual revenue covered

Originators in Edema

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Generic (originally Searle/Pfizer) 13 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating edema. Each bar = one year. Y-axis scaled to peak year (8 patents).

4
34
8
36
3
40

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Aldactone
spironolactone
 Generic (originally Searle/Pfizer) 8 50 — 2036-10-28
Bumex
BUMETANIDE
 — 4 70 — 2040-12-04
Lasix
furosemide
 Generic (originally Hoechst AG) 4 66 — 2034-04-03
Microzide
hydrochlorothiazide
 Generic (originally Merck) 1 75 — 2044-01-23

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
12370168 Lasix method of use 75 2034-04-03
11260038 Bumex method of use 75 2040-12-04
12329731 Bumex method of use 75 2040-12-04
11878022 Microzide method of use 75 2044-01-23
12558330 Bumex method of use 75 2045-05-14
11433044 Lasix method of use 70 2034-04-03
9884039 Lasix method of use 70 2034-04-03
11395828 Aldactone method of use 70 2036-10-28
9757394 Aldactone method of use 62 2036-10-28
11123319 Bumex formulation 55 2040-12-04

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
10493083 Aldactone formulation 42 2036-10-28
10624906 Aldactone formulation 42 2036-10-28
10888570 Aldactone formulation 42 2036-10-28
10660907 Aldactone formulation 42 2036-10-28
11491166 Aldactone formulation 50 2036-10-28
11389461 Aldactone formulation 50 2036-10-28
10272064 Lasix formulation 50 2034-04-03
11123319 Bumex formulation 55 2040-12-04
9757394 Aldactone method of use 62 2036-10-28
11395828 Aldactone method of use 70 2036-10-28

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