Cystic Fibrosis Of The Lung — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for cystic fibrosis of the lung. 433 active patents protecting 2 drugs from 2+ originators. First major cliff: 2026. Daily refresh.

2
Approved drugs
433
Active US patents
57/100
Avg vulnerability
—
Annual revenue covered

Originators in Cystic Fibrosis Of The Lung

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Vertex Pharms Inc 425 patents Bristol-Myers Squibb 8 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating cystic fibrosis of the lung. Each bar = one year. Y-axis scaled to peak year (114 patents).

69
26
114
27
34
28
72
29
58
30
22
31
7
32
54
33
3
35

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Kalydeco
IVACAFTOR
 Vertex Pharms Inc 425 50 — 2026-07-06
Acetadote
Acetylcysteine
 Bristol-Myers Squibb 8 64 — 2031-07-21

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8722738 Acetadote method of use 73 2032-04-06
8354427 Kalydeco method of use 71 2026-07-06
8354427 Kalydeco method of use 71 2026-07-06
7973038 Kalydeco method of use 71 2026-11-08
8741933 Kalydeco method of use 71 2026-11-08
9670163 Kalydeco method of use 71 2026-12-28
9670163 Kalydeco method of use 71 2026-12-28
9931334 Kalydeco method of use 71 2026-12-28
9670163 Kalydeco method of use 71 2026-12-28
11639347 Kalydeco method of use 71 2027-04-09

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
8507534 Kalydeco composition of matter 0 2030-09-20
8507534 Kalydeco composition of matter 0 2030-09-20
8507534 Kalydeco composition of matter 0 2030-09-20
8507534 Kalydeco composition of matter 0 2030-09-20
7776905 Kalydeco composition of matter 0 2027-06-03
7776905 Kalydeco composition of matter 0 2027-06-03
7495103 Kalydeco composition of matter 0 2027-05-20
7495103 Kalydeco composition of matter 0 2027-05-20
7495103 Kalydeco composition of matter 0 2027-05-20
7495103 Kalydeco composition of matter 0 2027-05-20

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