Last reviewed · How we verify
Chronic Pain with Opioid Tolerance
Approved treatments
- Dilaudid-Hp · Fresenius Kabi
Hydromorphone binds primarily to mu-opioid receptors, producing analgesia without a ceiling effect. - Subutex · Indivior
Buprenorphine is a partial agonist at mu-opioid receptors and antagonist at kappa-opioid receptors. - Fentanyl (F2) · Oslo University Hospital
- OxyContin · Purdue Pharma
- Naltrexon · Institute of Liver and Biliary Sciences, India
- Duragesic · Johnson & Johnson (Janssen Pharmaceutica)
Synthetic opioid 50-100x more potent than morphine that binds mu-opioid receptors, providing potent analgesia and anesthesia. - Subutex · Purdue Pharma Lp
Buprenorphine binds to mu-opioid receptors as a partial agonist and kappa-opioid receptors as an antagonist. - MS Contin · Generic (multiple manufacturers)
The prototypical opioid agonist that binds mu-opioid receptors in the CNS, providing potent analgesia and serving as the reference standard for all opioids. - Dilaudid-Hp · Fresenius Kabi
Full mu-opioid receptor agonist providing analgesia through CNS opioid receptor activation. - Duramorph Pf · Pfizer
Duramorph Pf works by binding to opioid receptors in the brain and spinal cord, mimicking the natural pain-relieving chemicals in the body. - Opana Er · Endo
- OXYCONTIN® · Mundipharma (China) Pharmaceutical Co. Ltd
OxyContin is a medication that works by binding to opioid receptors in the brain, altering the way the body perceives pain.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Chronic Pain with Opioid Tolerance patent landscape — cliff calendar, originator estates, attackable patents
- Chronic Pain with Opioid Tolerance treatment landscape brief
- Chronic Pain with Opioid Tolerance treatment updates RSS
Frequently asked questions about Chronic Pain with Opioid Tolerance
What drugs treat Chronic Pain with Opioid Tolerance?
Tracked treatments include Dilaudid-Hp, Subutex, Fentanyl (F2), OxyContin, Naltrexon, Duragesic, MS Contin, Duramorph Pf.
What is the treatment for Chronic Pain with Opioid Tolerance?
Standard treatment for Chronic Pain with Opioid Tolerance includes Dilaudid-Hp, Subutex, Fentanyl (F2), OxyContin, Naltrexon. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Chronic Pain with Opioid Tolerance patent cliff · Chronic Pain with Opioid Tolerance CI report
- Treatment: Dilaudid-Hp · Fresenius Kabi
- Treatment: Subutex · Indivior
- Treatment: Fentanyl (F2) · Oslo University Hospital
- Treatment: OxyContin · Purdue Pharma
- Treatment: Naltrexon · Institute of Liver and Biliary Sciences, India
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing