Chemotherapy Induced Nausea And Vomiting — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for chemotherapy induced nausea and vomiting. 58 active patents protecting 5 drugs from 5+ originators. First major cliff: 2029. Daily refresh.

5
Approved drugs
58
Active US patents
50/100
Avg vulnerability
—
Annual revenue covered

Originators in Chemotherapy Induced Nausea And Vomiting

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Merck & Co. 31 patents Helsinn Hlthcare 12 patents Hikma 7 patents GSK (originally Glaxo) 4 patents Wellhouse Pharma 4 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating chemotherapy induced nausea and vomiting. Each bar = one year. Y-axis scaled to peak year (31 patents).

4
27
4
28
7
29
10
30
1
31
31
35
1
38

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Emend
APREPITANT
 Merck & Co. 31 60 — 2027-09-26
Akynzeo
NETUPITANT
 Helsinn Hlthcare 12 47 — 2030-11-18
Reglan
Metoclopramide Hydrochloride
 Hikma 7 75 — 2029-12-22
Marinol
DRONABINOL
 Wellhouse Pharma 4 19 — 2028-08-06
Zofran
ondansetron
 GSK (originally Glaxo) 4 51 — 2029-11-23

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
12194009 Reglan method of use 81 2029-12-22
12194008 Reglan method of use 81 2029-12-22
12042494 Akynzeo method of use 81 2030-11-18
8258132 Emend method of use 80 2027-09-26
8258132 Emend method of use 80 2027-09-26
8258132 Emend method of use 80 2027-09-26
11813231 Reglan method of use 76 2029-12-22
11628150 Reglan method of use 76 2029-12-22
11559523 Akynzeo method of use 76 2030-11-18
8258132 Emend method of use 75 2027-09-26

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
10233154 Akynzeo composition of matter 4 2035-09-25
10676440 Akynzeo composition of matter 4 2035-09-25
10961195 Akynzeo composition of matter 4 2035-09-25
9951016 Akynzeo composition of matter 4 2035-09-25
9345771 Marinol composition of matter 17 2028-08-06
8222292 Marinol composition of matter 17 2028-08-06
10265293 Marinol composition of matter 17 2028-08-06
11253472 Marinol composition of matter 25 2028-08-06
9974793 Emend formulation 42 2035-09-18
10500208 Emend formulation 42 2035-09-18

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