Alk Fusion Gene Positive Non Small Cell Lung Cancer — Patent Landscape

Aggregated US Orange Book patent estate across every approved drug for alk fusion gene positive non small cell lung cancer. 21 active patents protecting 2 drugs from 2+ originators. First major cliff: 2033. Daily refresh.

2
Approved drugs
21
Active US patents
32/100
Avg vulnerability
—
Annual revenue covered

Originators in Alk Fusion Gene Positive Non Small Cell Lung Cancer

Companies holding active patents on drugs approved for this indication. Click through to each company's full patent dashboard.

Novartis 13 patents Pfizer 8 patents

Cliff calendar — next 15 years

Patent expiries per year across all drugs treating alk fusion gene positive non small cell lung cancer. Each bar = one year. Y-axis scaled to peak year (4 patents).

4
27
2
28
2
30
4
32
2
33
4
36
1
37
2
38

Approved drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Zykadia
ceritinib
 Novartis 13 34 — 2027-11-20
Lorbrena
lorlatinib
 Pfizer 8 30 — 2033-03-05

Most attackable patents

Highest vulnerability scores in the indication — paragraph IV / IPR / design-around candidates.

Patent Drug Type Vuln Expiry
8377921 Zykadia method of use 80 2027-11-20
8377921 Zykadia method of use 75 2027-11-20
12357630 Zykadia method of use 75 2037-12-13
8703787 Zykadia method of use 73 2032-02-02
8703787 Zykadia method of use 68 2032-02-02
10420749 Lorbrena method of use 62 2036-07-27
10420749 Lorbrena method of use 62 2036-07-27
11020376 Lorbrena formulation 42 2036-07-27
11020376 Lorbrena formulation 42 2036-07-27
7964592 Zykadia composition of matter 22 2028-04-29

Strongest defences

Lowest vulnerability scores — pillars of the indication's IP fortress.

Patent Drug Type Vuln Expiry
8680111 Lorbrena composition of matter 4 2033-03-05
8680111 Lorbrena composition of matter 4 2033-03-05
9309229 Zykadia composition of matter 10 2032-01-18
9309229 Zykadia composition of matter 10 2032-01-18
8039479 Zykadia composition of matter 10 2030-06-29
11299500 Lorbrena composition of matter 12 2038-10-04
11299500 Lorbrena composition of matter 12 2038-10-04
8039479 Zykadia composition of matter 15 2030-06-29
7964592 Zykadia composition of matter 17 2028-04-29
8399450 Zykadia composition of matter 17 2027-11-20

Related