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Acute lymphoid leukemia
Approved treatments
- Oncovin · University of Colorado, Denver
- Solu-Cortef · Pfizer
- Vincristin · Arbeitsgemeinschaft medikamentoese Tumortherapie
- Daunorubicin Hydrochloride · Meiji Seika Pharma Co., Ltd
- Cortifoam · Pfizer
- Cortone
- Celestone Soluspan
- Decadron · Generic (originally Merck)
- Vindesin · The Lymphoma Academic Research Organisation
- Daunorubicine · Gruppo Italiano Malattie EMatologiche dell'Adulto
- Cytarabine · Nippon Shinyaku Co., Ltd.
Cytarabine inhibits DNA polymerase and incorporates into DNA/RNA, killing cells in S-phase. - 6-Mercaptopurine · Pfizer Inc.
- adriacin · Chipscreen Biosciences, Ltd.
- Hydroxydaunorubicin · University of Colorado, Denver
- Erwinase · M.D. Anderson Cancer Center
- Oncaspar · Dana-Farber Cancer Institute
- prednison · Wen Zhang
- Medrol · Generic (originally Upjohn/Pfizer)
Potent synthetic glucocorticoid with 5x hydrocortisone potency and minimal mineralocorticoid activity, used for severe inflammatory conditions. - Cortef · Generic (originally Merck/Upjohn)
- Eldisine
- Rodinolone
- Deltasone · Generic (originally Schering)
- Erwinase · Jazz Pharms Inc
- Purixan · Stason Pharms
Purixan works by inhibiting the enzyme responsible for producing prostaglandins, which are involved in inflammation and immune response. - Oncovin · Pfizer Inc.
- Oncovin · Pfizer Inc.
- Elspar · Merck & Co.
RYLAZE kills leukemic cells by depleting plasma asparagine, which they need for survival. - Liposomal Doxorubicin · Pfizer
- Clolar · Sanofi
Clolar works by inhibiting the enzyme responsible for DNA synthesis, thereby preventing cancer cells from reproducing. - Betametasone
Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system. - Doxorubicin Hydrochloride · Pfizer
Doxorubicin works by intercalating DNA strands and inhibiting topoisomerase II, an enzyme essential for DNA replication and cell division. - Trexall · Generic (originally Lederle Laboratories)
Antifolate that inhibits dihydrofolate reductase (DHFR), blocking DNA synthesis at high doses (oncology) and suppressing inflammation at low doses (autoimmune). - Methotrexat · Biocad
- Cortisol · University of Zurich
- Prelone · Generic (originally Schering)
- Hydroxydaunomycin · Weill Medical College of Cornell University
- prednisolon · Hannover Medical School
- Adriamycin · Johann Wolfgang Goethe University Hospital
- Methylprednisolon · Leiden University Medical Center
- Xaluprine · Kjeld Schmiegelow
Clinical guidelines
- FDA label — 1L
Cytarabine Injection in combination with other approved anticancer drugs is indicated for remission induction. - FDA label — 1L
Cytarabine Injection in combination with other approved anticancer drugs is indicated for remission induction. - FDA label — 1L
Cytarabine Injection in combination with other approved anticancer drugs is indicated for remission induction. - FDA label — 1L
Dexamethasone is indicated for the palliative management of leukemias and lymphomas. - FDA label — any
Prednisolone is indicated for the treatment of acute lymphoid leukemia. - FDA label — 1L
Vincristine Sulfate Injection is indicated in acute leukemia. - FDA label — adj
Methylprednisolone can be used as part of combination chemotherapy regimens for the treatment of acute lymphoid leukemia.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Acute lymphoid leukemia patent landscape — cliff calendar, originator estates, attackable patents
- Acute lymphoid leukemia treatment landscape brief
- Acute lymphoid leukemia treatment updates RSS
Frequently asked questions about Acute lymphoid leukemia
What drugs treat Acute lymphoid leukemia?
Tracked treatments include Oncovin, Solu-Cortef, Vincristin, Daunorubicin Hydrochloride, Cortifoam, Cortone, Celestone Soluspan, Decadron.
What is the treatment for Acute lymphoid leukemia?
Standard treatment for Acute lymphoid leukemia includes Oncovin, Solu-Cortef, Vincristin, Daunorubicin Hydrochloride, Cortifoam. See the treatment landscape page for first-line, second-line and salvage options.
What are the treatment guidelines for Acute lymphoid leukemia?
FDA label publishes guidelines for Acute lymphoid leukemia. 7 guideline references tracked.
Related
- Treatment landscape: Acute lymphoid leukemia patent cliff · Acute lymphoid leukemia CI report
- Treatment: Oncovin · University of Colorado, Denver
- Treatment: Solu-Cortef · Pfizer
- Treatment: Vincristin · Arbeitsgemeinschaft medikamentoese Tumortherapie
- Treatment: Daunorubicin Hydrochloride · Meiji Seika Pharma Co., Ltd
- Treatment: Cortifoam · Pfizer
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing