Wegovy ® vs Zepbound

Side-by-side comparison of Wegovy ® and Zepbound — mechanism, indications, safety, trials, sponsor, and pricing.

At a glance

Wegovy ®Zepbound
Generic nameWegovy ®Zepbound
SponsorHangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.The University of Texas Medical Branch, Galveston
ModalitySmall moleculeSmall molecule
PhaseFDA-approvedFDA-approved
Therapeutic area—Other

Mechanism of action

Wegovy ®—
Zepbound—

Approved indications

Wegovy ®

None tracked.

Zepbound

None tracked.

Common side effects

Wegovy ®

None on file.

Zepbound

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Abdominal pain
  • Dyspepsia
  • Injection site reactions
  • Fatigue

Boxed warnings

Wegovy ®

No boxed warnings.

Zepbound

  • WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether ZEPBOUND causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions ( 5.1 ) and Nonclinical Toxicology ( 13.1 )]. ZEPBOUND is contraindicated in patients wi

Further reading