Ozempic® vs Wegovy ®
Side-by-side comparison of Ozempic® and Wegovy ® — mechanism, indications, safety, trials, sponsor, and pricing.
At a glance
| Ozempic® | Wegovy ® |
| Generic name | Ozempic® | Wegovy ® |
| Sponsor | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. |
| Drug class | GLP-1 receptor agonist | — |
| Molecular target | GLP-1R (glucagon-like peptide-1 receptor) | — |
| Modality | Small molecule | Small molecule |
| Phase | FDA-approved | FDA-approved |
| Therapeutic area | Diabetes | — |
Mechanism of action
| Ozempic® | Ozempic activates GLP-1 receptors to increase insulin secretion, slow gastric emptying, and reduce appetite, thereby lowering blood glucose levels in type 2 diabetes. |
| Wegovy ® | — |
Approved indications
Ozempic®
- Type 2 diabetes mellitus
- Cardiovascular risk reduction in patients with type 2 diabetes and established cardiovascular disease
Common side effects
Ozempic®
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal pain
- Hypoglycemia
Further reading