Jiangsu Simcere Pharmaceutical Co., Ltd.
Quick facts
Marketed products
- Levamlodipine besylate · Cardiovascular
Levamlodipine besylate is the active L-enantiomer of amlodipine that blocks L-type calcium channels in vascular smooth muscle and cardiac tissue, causing vasodilation and reducing blood pressure.
Phase 3 pipeline
- Bendamustine hydrochloride injection · Oncology
Bendamustine is an alkylating agent that cross-links DNA strands, causing cell death in rapidly dividing cancer cells. - Compound Edaravone Injection · Neurology
Edaravone is a free radical scavenger that reduces oxidative stress and neuronal damage by neutralizing hydroxyl radicals and other reactive oxygen species. - ENDOSTAR，cisplatin · Oncology
Endostar is a recombinant human endostatin that inhibits angiogenesis by blocking new blood vessel formation, used in combination with cisplatin chemotherapy to treat solid tumors. - Endostar continuous intravenous infusion · Oncology
Endostar is a recombinant human endostatin that inhibits angiogenesis by blocking new blood vessel formation in tumors. - Endostar routine intravenous infusion · Oncology
Endostar is a recombinant human endostatin that inhibits angiogenesis by blocking new blood vessel formation in tumors. - placebo, carboplatin, etoposide，or Topotecan · Oncology
Carboplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - Placebo , cisplatin · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication and induce apoptosis. - SIM0270
SIM0270 is a small molecule inhibitor targeting a specific molecular pathway involved in disease pathogenesis, though the exact mechanism requires further clarification. - Suvemcitug injection, trifluridine/tipiracil tablets · Oncology
Trifluridine/tipiracil is a nucleoside analog combination that inhibits thymidylate synthase and incorporates into DNA to induce apoptosis in cancer cells. - Trilaciclib, carboplatin, etoposide，or Topotecan · Oncology
Trilaciclib is a CDK4/6 inhibitor that blocks cell cycle progression.
Phase 2 pipeline
- Docetaxel Polymeric Micelles for Injection · Oncology
Docetaxel inhibits microtubule dynamics by stabilizing microtubules and preventing their depolymerization. - Fluorouracil Implants · Oncology
Fluorouracil implants work by releasing fluorouracil, a thymidylate synthase inhibitor, which interferes with DNA synthesis and function. - SIM0417
- Xelox regimes
Phase 1 pipeline
- [14C] SIM0270 Oral Preparation
- dose expansion of SIM0609 in CRC
- dose expansion of SIM0609 in PDAC cohort
- Metatinib Tromethamine
- SCR-6920 capsule
- Sevacizumab · Other
- SIM0237
- SIM0237 and BCG
- SIM0348
- SIM0388
- SIM0500
- SIM0508 in combination with olaparib
- SIM0508 Tablets
- SIM0686
- SIM0811
- SIM1803-1A
- SIM1811-03
- SIM1910-09
- Simotinib Hydrochloride
- SSD8432 dose 1~7 and Ritonavir
- SSD8432 dose 10~12 and ritonavir
- SSD8432 dose 13 and Ritonavir
- SSD8432 dose 8~9
Competitive intelligence
For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors: