H. Lundbeck A/S

Quick facts

Marketed products

• Azilect®
• Droxidopa capsules
• Memantine (once daily) · Neurology
  Memantine is an uncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor that reduces excessive glutamate-mediated neuronal excitotoxicity.
• Memantine (twice daily) · Neurology
  Memantine is an uncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor that blocks excessive glutamate signaling in the brain.
• Zerdol · Neuroscience

Phase 3 pipeline

• Adjunct brexpiprazole · Psychiatry
  Brexpiprazole is a serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, used as an adjunctive treatment to enhance antidepressant efficacy.
• Aripiprazole and aripiprazole once-monthly · Psychiatry
  Aripiprazole is a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, and an antagonist at serotonin 5-HT2A receptors, which stabilizes dopamine and serotonin neurotransmission in the brain.
• Lu AA21004 · Psychiatry/Neurology
  Lu AA21004 is a multimodal antidepressant that acts as a serotonin reuptake inhibitor, serotonin 5-HT1A receptor agonist, and serotonin 5-HT7 receptor antagonist.
• MK0928, gaboxadol · Neurology / Sleep Medicine
  Gaboxadol is a selective GABA-A receptor agonist that enhances inhibitory neurotransmission in the central nervous system.
• Paliperidone and paliperidone palmitate · Psychiatry/Neurology
  Paliperidone is an atypical antipsychotic that blocks dopamine D2 and serotonin 5-HT2A receptors in the brain to reduce psychotic symptoms.
• Vortioxetine (Lu AA21004) · Psychiatry
  Vortioxetine is a serotonin modulator and stimulator that acts as a selective 5-HT3 receptor antagonist, 5-HT1A receptor agonist, 5-HT7 receptor agonist, and norepinephrine reuptake inhibitor.

Phase 2 pipeline

• Lu AA24493
• Lu AA24530 · Neurology
  Selective 5-HT6 receptor antagonist
• Lu AE58054
• Lu AF82422
• Lu AG09222
• Lu AG13909
• Vortioxetine IV

Phase 1 pipeline

• [11C]-Lu AF88370
• [11C]-Lu AF88434
• [11C]-Lu AF90103
• [11C]PXT012253
• [14C]-Lu AF11167
• [14C]-Lu AG06466
• ALD1910
• [benzyl-7-14C]-idalopirdine
• Cohort B1: Lu AE58054
• Eptinezumab Mammalian Cell Line
• Eptinezumab Yeast Cell Line
• [ethyl-1-14C]-idalopirdine
• Immune System Activator
• Lactose-free memantine
• ldalopirdine 120 mg
• Lu AF28996
• Lu AF35700 iv
• Lu AF76432
• Lu AF87908
• Lu AF88434
• Lu AG22515
• Part A: Lu AF35700
• Part B: Lu AF35700
• Vortioxetine SLA
• Vortioxetine SLB
• Vortioxetine SLC

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• H. Lundbeck A/S portfolio CI brief
• H. Lundbeck A/S pipeline updates RSS