European Organisation for Research and Treatment of Cancer - EORTC
2 marketed ·
11 in Phase 3
Quick facts
Marketed products
FLOT · Oncology FLOT is a chemotherapy regimen combining fluorouracil, leucovorin, oxaliplatin, and docetaxel to inhibit DNA synthesis and microtubule formation, killing rapidly dividing cancer cells.
Pertuzumab + trastuzumab · Oncology Pertuzumab and trastuzumab are monoclonal antibodies that block HER2 signaling by binding to different epitopes on the HER2 receptor, preventing ligand-induced dimerization and receptor activation.
Phase 3 pipeline
177Lu-PSMA-617 · Oncology 177Lu-PSMA-617 is a radioligand that binds to prostate-specific membrane antigen (PSMA) on cancer cells and delivers targeted radiation therapy to kill PSMA-expressing tumors.
ABVD q4 weeks · Oncology ABVD is a combination chemotherapy regimen that uses four cytotoxic agents to kill rapidly dividing cancer cells through multiple mechanisms including DNA alkylation, topoisomerase inhibition, and microtubule disruption.
BEACOPP escalated q3 weeks · Oncology BEACOPP escalated is a multi-drug chemotherapy regimen that combines bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone at escalated doses to kill rapidly dividing cancer cells.
cMAB · Oncology cMAB is a monoclonal antibody targeting the PD-1 receptor.
GM2-KLH vaccine · Oncology GM2-KLH vaccine stimulates the immune system to recognize and attack cancer cells expressing the GM2 ganglioside antigen on their surface.
iMAB · Oncology iMAB is an investigational immunomodulatory antibody designed to enhance anti-tumor immune responses.
ISIS 3521 · Oncology ISIS 3521 is an antisense oligonucleotide that inhibits protein kinase C-alpha (PKC-alpha) expression to suppress cancer cell proliferation and survival.
monoclonal antibody BEC2 · Oncology BEC2 is a monoclonal antibody that targets GD3 ganglioside on tumor cell surfaces to trigger immune-mediated destruction of cancer cells.
Ra223 · Oncology Ra223 is an alpha-emitting radiopharmaceutical that targets bone metastases and delivers localized radiation to kill cancer cells.