Chinese Academy of Medical Sciences

Quick facts

Marketed products

• Idarubicin(IDA) · Oncology
  Idarubicin is a topoisomerase II inhibitor that intercalates into DNA and prevents DNA unwinding, leading to cell death in rapidly dividing cancer cells.
• live attenuated Japanese encephalitis vaccine · Immunology
  This live attenuated vaccine stimulates immune responses against Japanese encephalitis virus by introducing a weakened form of the virus that replicates but does not cause disease.
• MSC+ATG · Other
• OM-85 BV · Immunology / Infectious Disease
  OM-85 BV is a bacterial lysate immunostimulant that enhances innate and adaptive immune responses to prevent respiratory tract infections.
• pemetrexed plus cisplatin
• singular · Other
• two measles attenuated live vaccine

Phase 3 pipeline

• Active Comparator: FOLFOX plus cetuximab · Oncology
  FOLFOX plus cetuximab combines chemotherapy with an EGFR-targeting monoclonal antibody to kill colorectal cancer cells through dual mechanisms of DNA damage and growth factor receptor inhibition.
• Adjuvant chemotherapy for experimental group · Oncology
  Adjuvant chemotherapy uses cytotoxic drugs administered after primary treatment to eliminate residual cancer cells and reduce recurrence risk.
• bOPV(Candy) · Infectious Diseases
  bOPV(Candy) is a vaccine that targets the SARS-CoV-2 virus.
• bOPV(Liquid) · Infectious Diseases
  bOPV is a live attenuated vaccine.
• Camrelizumab and Apatinib · Oncology
  Camrelizumab blocks PD-1 to enhance immune response while apatinib inhibits VEGFR2 to suppress tumor angiogenesis, combining immunotherapy with anti-angiogenic effects.
• Docetaxel;oxaliplatin;s1 · Oncology
  This combination regimen uses three chemotherapy agents—docetaxel (microtubule stabilizer), oxaliplatin (platinum crosslinker), and S-1 (fluoropyrimidine)—to attack cancer cells through multiple mechanisms simultaneously.
• Epirubicin, CTX, Paclitaxel · Oncology
  This is a combination chemotherapy regimen where epirubicin and paclitaxel are topoisomerase II and microtubule-targeting agents respectively, used together to inhibit cancer cell division and induce apoptosis.
• Epirubicin, Paclitaxel · Oncology
  Epirubicin and paclitaxel are chemotherapy agents that work together to inhibit cancer cell division and induce apoptosis through different mechanisms.
• Experimental: mXELOX plus cetuximab · Oncology
  mXELOX plus cetuximab combines modified capecitabine/oxaliplatin chemotherapy with an EGFR-targeting monoclonal antibody to inhibit tumor cell proliferation and survival.
• Irinotecan Injection · Oncology
  Irinotecan is a topoisomerase I inhibitor that prevents DNA religation during replication, leading to DNA damage and cancer cell death.
• filgrastim and pegylated filgrastim · Oncology
  Filgrastim and pegylated filgrastim stimulate the production of white blood cells, specifically neutrophils, to help the body fight infection.
• oxaliplatin;s1 · Oncology
  Oxaliplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription.
• Paclitaxel and carboplatin · Oncology
  Paclitaxel and carboplatin work together as a chemotherapy combination: paclitaxel stabilizes microtubules to prevent cell division, while carboplatin cross-links DNA to cause cell death.
• pegylated filgrastim and filgrastim · Oncology
  Pegylated filgrastim and filgrastim stimulate the production of white blood cells, specifically neutrophils, to help the body fight infection.
• Platinum-Based Drug · Oncology
  Platinum-based drugs form covalent crosslinks with DNA, preventing replication and transcription to induce cancer cell death.

Phase 2 pipeline

• EC-T

Phase 1 pipeline

• Anlotinib combined with paclitaxel and carboplatin, phase I
• Anlotinib combined with pemetrexed and carboplatin, phase II

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• Chinese Academy of Medical Sciences portfolio CI brief
• Chinese Academy of Medical Sciences pipeline updates RSS

Frequently asked questions about Chinese Academy of Medical Sciences

Related

• Idarubicin(IDA) · Oncology
• live attenuated Japanese encephalitis vaccine · Immunology
• MSC+ATG · Other
• OM-85 BV · Immunology / Infectious Disease
• pemetrexed plus cisplatin
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