Vasodilator combination
This page covers all Vasodilator combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Nitric oxide pathway; vascular smooth muscle, Vascular smooth muscle (hydralazine); soluble guanylate cyclase (isosorbide dinitrate).
Targets
Nitric oxide pathway; vascular smooth muscle · Vascular smooth muscle (hydralazine); soluble guanylate cyclase (isosorbide dinitrate)
Marketed (2)
- Isosorbide Dinitrate + Hydralazine · Corporal Michael J. Crescenz VA Medical Center · Cardiovascular
Isosorbide dinitrate provides nitric oxide to relax blood vessels, while hydralazine directly relaxes vascular smooth muscle, together reducing cardiac preload and afterload to improve heart function. - Hydralazine/Isorsorbide Dinitrate · Brigham and Women's Hospital · Cardiovascular
Hydralazine relaxes blood vessel smooth muscle while isosorbide dinitrate provides nitric oxide to dilate vessels, together reducing cardiac afterload and preload to improve heart function.