TNF receptor antagonist

This page covers all TNF receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting TNF-α and TNF-β.

Targets

TNF-α and TNF-β

Marketed (2)

• Etanercept (ENBREL®) · Amgen · Immunology
  Etanercept is a TNF receptor fusion protein that binds and neutralizes tumor necrosis factor (TNF), a key inflammatory cytokine driving immune-mediated diseases.
• Yisaipu® · Nanfang Hospital, Southern Medical University · Immunology / Rheumatology
  Yisaipu is a recombinant human TNF receptor II-IgG fusion protein that binds and neutralizes tumor necrosis factor (TNF) to reduce inflammatory responses.

Phase 3 pipeline (2)

• Commercial Formulation Etanercept · Amgen · Immunology
  Etanercept is a TNF receptor fusion protein that binds and neutralizes tumor necrosis factor (TNF), a key inflammatory cytokine.
• Etanercept Liquid · Amgen · Immunology
  Etanercept is a TNF receptor fusion protein that binds and neutralizes tumor necrosis factor (TNF), a key inflammatory cytokine.