TNF blocker

This page covers all TNF blocker drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Tumor necrosis factor-alpha (TNF-alpha), Tumor Necrosis Factor alpha (TNFα), Tumor Necrosis Factor-alpha (TNF-alpha).

Targets

Tumor necrosis factor-alpha (TNF-alpha) · Tumor Necrosis Factor alpha (TNFα) · Tumor Necrosis Factor-alpha (TNF-alpha)

Marketed (3)

• Abrilada · AbbVie · Oncology · 10191
  Adalimumab-afzb binds TNF-alpha and blocks interaction with p55 and p75 cell surface receptors.
• Remicade · Johnson & Johnson · Oncology
  Infliximab-dyyb neutralizes TNFα by binding with high affinity to soluble and transmembrane forms, inhibiting receptor binding.
• Humira · AbbVie · Oncology
  Adalimumab binds TNF-alpha and blocks interaction with p55 and p75 cell surface receptors.