Thiazide-like diuretic plus potassium-sparing diuretic combination
This page covers all Thiazide-like diuretic plus potassium-sparing diuretic combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Na-Cl cotransporter (chlorthalidone); epithelial sodium channel ENaC (amiloride).
Targets
Na-Cl cotransporter (chlorthalidone); epithelial sodium channel ENaC (amiloride)
Phase 3 pipeline (1)
- Chlorthalidone plus amiloride · Hospital de Clinicas de Porto Alegre · Cardiovascular
Chlorthalidone is a thiazide-like diuretic that reduces sodium reabsorption in the distal convoluted tubule, while amiloride is a potassium-sparing diuretic that blocks sodium channels in the collecting duct, together lowering blood pressure and reducing fluid overload.
Patent intelligence
- thiazide like diuretic plus potassium sparing diuretic combination patent landscape — aggregated cliff calendar, attackable patents, originator estates