Sulfone antimicrobial and anti-inflammatory agent

This page covers all Sulfone antimicrobial and anti-inflammatory agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Dihydrofolate reductase; neutrophil function modulation, Dihydropteroate synthase; neutrophil function modulation.

Targets

Dihydrofolate reductase; neutrophil function modulation · Dihydropteroate synthase; neutrophil function modulation

Marketed (1)

• Dapsone gel, 5% · Vanderbilt University Medical Center · Dermatology
  Dapsone is a sulfone antimicrobial and anti-inflammatory agent that inhibits bacterial dihydrofolate reductase and suppresses neutrophil function and reactive oxygen species production.

Phase 3 pipeline (1)

• Dapsone Topical Gel + vehicle control · Allergan · Dermatology
  Dapsone is a sulfone antimicrobial and anti-inflammatory agent that inhibits bacterial folate synthesis and suppresses neutrophil function to reduce inflammation in acne.