Pyruvate kinase activator

This page covers all Pyruvate kinase activator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Pyruvate kinase R (PKR).

Targets

Pyruvate kinase R (PKR)

Phase 3 pipeline (2)

• Placebo Matching Mitapivat · Agios Pharmaceuticals, Inc. · Hematology
  Mitapivat activates pyruvate kinase R (PKR), an enzyme that increases ATP production in red blood cells to improve their survival and function.
• AG-348 · Agios Pharmaceuticals, Inc. · Hematology
  AG-348 activates pyruvate kinase R (PKR), an enzyme that increases ATP production in red blood cells to improve their survival and reduce hemolysis.