Potassium-sparing diuretic

This page covers all Potassium-sparing diuretic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Epithelial sodium channel (ENaC), Amiloride-sensitive sodium channel, ENaC.

Targets

Epithelial sodium channel (ENaC) · Amiloride-sensitive sodium channel, ENaC

Marketed (2)

• Anhydrous Amiloride Hydrochloride · Assistance Publique - Hôpitaux de Paris · Cardiovascular
  Amiloride is a potassium-sparing diuretic that blocks sodium reabsorption in the collecting duct of the nephron, thereby increasing sodium and water excretion while retaining potassium.
• Midamor · Padagis Us · Immunology

Phase 2 pipeline (1)

• Betmiga® · Astellas Pharma Europe Ltd. · Urology
  Betmiba works by increasing the levels of magnesium in the urine, which helps to prevent kidney stones.