Peripheral mu-opioid receptor antagonist

This page covers all Peripheral mu-opioid receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Mu-opioid receptor (peripheral).

Targets

Mu-opioid receptor (peripheral)

Marketed (1)

• Methylnaltrexone (MNTX) · Bausch Health Americas, Inc. · Gastroenterology / Pain Management
  Methylnaltrexone is a peripheral mu-opioid receptor antagonist that blocks opioid receptors in the gastrointestinal tract without crossing the blood-brain barrier, thereby reversing opioid-induced constipation.

Phase 3 pipeline (2)

• Methylnaltrexone (MOA-728) · Bausch Health Americas, Inc. · Gastroenterology / Supportive Care
  Methylnaltrexone is a peripheral mu-opioid receptor antagonist that blocks opioid receptors in the gastrointestinal tract without crossing the blood-brain barrier, thereby reversing opioid-induced constipation while preserving central analgesia.
• SC Methylnaltrexone (MNTX) · Bausch Health Americas, Inc. · Gastroenterology / Supportive Care
  Methylnaltrexone is a peripheral mu-opioid receptor antagonist that blocks opioid receptors in the gastrointestinal tract without crossing the blood-brain barrier, thereby reversing opioid-induced constipation.