What are Peptide hormone drugs?

Peptide hormone drugs are pharmacologic agents that share a common mechanism (typically targeting Melanocortin-2 receptor (MC2R)). 0 are currently marketed, with 4 more in clinical development.

Peptide hormone

0 marketed 4 in Phase 3

This page covers all Peptide hormone drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Melanocortin-2 receptor (MC2R), Insulin receptor (INSR), Oxytocin receptor (OXTR).

Targets

Melanocortin-2 receptor (MC2R) · Insulin receptor (INSR) · Oxytocin receptor (OXTR) · Somatostatin receptors (SSTR1, SSTR2, SSTR3, SSTR4, SSTR5)

Phase 3 pipeline (4)

Adrenocorticotrophic hormone · University of Ottawa · Endocrinology / Immunology
Adrenocorticotrophic hormone (ACTH) stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.
Insulin therapy · Shanghai Jiao Tong University School of Medicine · Endocrinology / Diabetes
Insulin therapy replaces or supplements the body's own insulin to regulate blood glucose by promoting glucose uptake into cells and storage as glycogen.
Intravenous Oxytocin · University of Wisconsin, Madison · Obstetrics and Gynecology
Intravenous oxytocin is a synthetic peptide hormone that binds to oxytocin receptors to stimulate uterine contractions and promote milk letdown during lactation.
somatostatin infusion · Hospices Civils de Lyon · Gastroenterology
Somatostatin infusion activates somatostatin receptors on neuroendocrine and immune cells to inhibit hormone and cytokine secretion and reduce splanchnic blood flow.