What are Organ preservation solution drugs?

Organ preservation solution drugs are pharmacologic agents that share a common mechanism (typically targeting Reactive oxygen species (ROS), particularly hydroxyl radicals). 2 are currently marketed, with 3 more in clinical development.

What are the marketed Organ preservation solution drugs?

Marketed Organ preservation solution drugs include Custodiol Htk Soln, HTK Custodiol.

Organ preservation solution

2 marketed 3 in Phase 3

This page covers all Organ preservation solution drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Reactive oxygen species (ROS), particularly hydroxyl radicals.

Targets

Reactive oxygen species (ROS), particularly hydroxyl radicals

Marketed (2)

Custodiol Htk Soln · Lourdes Montero Cruces · Transplantation
Custodiol HTK is an organ preservation solution that maintains cellular viability during cold storage by providing essential electrolytes, buffers, and metabolic substrates while minimizing ischemic injury.
HTK Custodiol · Rigshospitalet, Denmark · Transplantation
HTK Custodiol is an organ preservation solution that maintains cellular viability during cold storage by providing essential electrolytes, buffers, and substrates while minimizing ischemic injury.

Phase 3 pipeline (3)

Custodiol HTK · Marc Sakwa, MD · Transplantation
Custodiol HTK is an organ preservation solution that maintains cellular viability and reduces ischemic injury during organ transplantation by providing a balanced electrolyte composition and metabolic substrates.
Custodiol-N · Dr. F. Köhler Chemie GmbH · Transplantation
Custodiol-N is an organ preservation solution that maintains cellular viability and reduces ischemic injury during organ transplantation by providing essential electrolytes, substrates, and buffering capacity.
Hydrogen-Rich Celsior Solution · RenJi Hospital · Transplantation/Organ Preservation
Hydrogen-rich Celsior solution reduces ischemic reperfusion injury by providing antioxidant protection through molecular hydrogen during organ preservation and transplantation.