What are Oncolytic virus drugs?

Oncolytic virus drugs are pharmacologic agents that share a common mechanism (typically targeting Tumor cells (HSV-tk prodrug activation pathway)). 0 are currently marketed, with 3 more in clinical development.

Oncolytic virus

0 marketed 3 in Phase 3

This page covers all Oncolytic virus drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Tumor cells (HSV-tk prodrug activation pathway).

Targets

Tumor cells (HSV-tk prodrug activation pathway)

Phase 3 pipeline (3)

AdV-tk · Candel Therapeutics, Inc. · Oncology
AdV-tk is an oncolytic adenovirus expressing herpes simplex virus thymidine kinase that replicates in tumor cells and sensitizes them to ganciclovir, triggering both direct viral lysis and immune activation.
rAd-IFN · Ferring Ventures Limited · Oncology
rAd-IFN is a recombinant adenovirus vector-based gene therapy that expresses interferon-alpha.
Virulizin® · Aptose Biosciences Inc. · Oncology
Virulizin is an oncolytic virus therapy that selectively infects and destroys cancer cells while sparing normal tissue.