Mood stabilizer combination

This page covers all Mood stabilizer combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Lithium: inositol monophosphatase and GSK-3β; Carbamazepine: voltage-gated sodium channels, GSK-3, inositol monophosphatase, histone deacetylase, GABA signaling.

Targets

Lithium: inositol monophosphatase and GSK-3β; Carbamazepine: voltage-gated sodium channels · GSK-3, inositol monophosphatase, histone deacetylase, GABA signaling

Marketed (2)

• lithium plus carbamazepine · University of Sao Paulo · Psychiatry
  Lithium and carbamazepine together modulate mood through distinct mechanisms: lithium alters intracellular signaling and neurotransmitter activity, while carbamazepine acts as a sodium channel blocker and anticonvulsant.
• lithium plus valproate · University of Sao Paulo · Psychiatry
  Lithium and valproate together modulate neuronal signaling and gene expression through distinct pathways to stabilize mood and reduce manic or depressive episodes.