What are Menin inhibitor drugs?

Menin inhibitor drugs are pharmacologic agents that share a common mechanism (typically targeting Menin (MEN1)). 0 are currently marketed, with 3 more in clinical development.

Menin inhibitor

0 marketed 3 in Phase 3

This page covers all Menin inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Menin (MEN1), Menin (MEN1 protein).

Targets

Menin (MEN1) · Menin (MEN1 protein)

Phase 3 pipeline (3)

BMS-986365 · Celgene · Oncology
BMS-986365 is a selective inhibitor of menin that disrupts the interaction between menin and mixed-lineage leukemia (MLL) proteins, restoring normal gene expression in leukemic cells.
BGB-15025 · BeiGene · Oncology
BGB-15025 is a selective inhibitor of menin that disrupts the interaction between menin and mixed-lineage leukemia (MLL) proteins, restoring normal gene expression in acute leukemias.
MK-8527 · Merck Sharp & Dohme LLC · Oncology
MK-8527 is a selective inhibitor of menin that restores wild-type p53 function in TP53-mutant cancers by disrupting the menin-MLL interaction.