Macrocyclic antibiotic

This page covers all Macrocyclic antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial RNA polymerase (C. difficile), Bacterial RNA polymerase.

Targets

Bacterial RNA polymerase (C. difficile) · Bacterial RNA polymerase

Phase 3 pipeline (3)

• Fidaxomicin oral suspension · Astellas Pharma Europe B.V. · Infectious Disease
  Fidaxomicin is a macrocyclic antibiotic that inhibits bacterial RNA polymerase, selectively killing Clostridioides difficile while minimizing effects on normal gut flora.
• OPT-80 · Astellas Pharma Inc · Infectious Disease
  OPT-80 is a macrocyclic antibiotic that inhibits bacterial protein synthesis by binding to the bacterial ribosome.
• Fidaxomicin tablets · Astellas Pharma Europe B.V. · Infectious Disease
  Fidaxomicin is a macrocyclic antibiotic that inhibits bacterial RNA polymerase, selectively killing Clostridioides difficile while minimizing effects on normal gut flora.