Iron chelator

This page covers all Iron chelator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Ferric iron (Fe³⁺), Ferric iron (Fe³⁺) and ferrous iron (Fe²⁺), Deoxyhypusine hydroxylase.

Targets

Ferric iron (Fe³⁺) · Ferric iron (Fe³⁺) and ferrous iron (Fe²⁺) · Deoxyhypusine hydroxylase · Iron · Iron ions

Marketed (6)

• Captafer® · American University of Beirut Medical Center · Hematology
  Captafer is an iron-chelating agent that binds and removes excess iron from the body to treat iron overload conditions.
• deferiprone matching placebo tablets · ApoPharma · Hematology
  Deferiprone is an iron chelator that binds and removes excess iron from the body, reducing iron-induced tissue damage.
• Desferal (deferoxamine) · ApoPharma · Hematology
  Deferoxamine is an iron chelator that binds free iron in the body and facilitates its excretion through urine and feces.
• Deferiprone (DFP) · Azienda Ospedaliera V. Cervello · Hematology
  Deferiprone is an iron chelator that binds and removes excess iron from the body, reducing iron-induced tissue damage.
• Ferriprox (deferiprone) · ApoPharma · Hematology
  Deferiprone is an iron chelator that binds excess iron in the body and facilitates its excretion through urine.
• Desferal · Mitem Pharma · Hematology

Phase 3 pipeline (1)

• Deferoxamine mesylate only · The George Institute · Hematology
  Deferoxamine mesylate is an iron chelator that binds free iron and removes it from the body through urinary and fecal excretion.

Phase 2 pipeline (3)

• CRMD-001-Deferiprone · CorMedix · Rare Disease
  Iron chelator
• Deferiprone, dose level 2 · Consorzio per Valutazioni Biologiche e Farmacologiche · Oncology
  Iron chelator
• Deferiprone, dose level 3 · Consorzio per Valutazioni Biologiche e Farmacologiche · Hematology
  Deferiprone chelates iron, reducing its accumulation in tissues.