What are Intravenous sedative-hypnotic drugs?

Intravenous sedative-hypnotic drugs are pharmacologic agents that share a common mechanism (typically targeting GABA-A receptor). 6 are currently marketed, with 1 more in clinical development.

What are the marketed Intravenous sedative-hypnotic drugs?

Marketed Intravenous sedative-hypnotic drugs include total intravenous anaesthesia with Propofol., Manual titration of propofol, Propofol Injection, Administering propofol, Sedation Propofol, Propofol as induction agent.

Intravenous sedative-hypnotic

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

6 marketed 1 in Phase 3

This page covers all Intravenous sedative-hypnotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting GABA-A receptor.

Targets

GABA-A receptor

Marketed (6)

total intravenous anaesthesia with Propofol. · Centre Hospitalier Universitaire Dijon · Anesthesiology
Propofol is a rapid-acting intravenous sedative-hypnotic that enhances inhibitory GABA neurotransmission in the central nervous system to produce unconsciousness and anesthesia.
Manual titration of propofol · Brugmann University Hospital · Anesthesia
Propofol is an intravenous sedative-hypnotic agent that enhances inhibitory GABAergic neurotransmission in the central nervous system to produce sedation and anesthesia.
Propofol Injection · Second Affiliated Hospital, School of Medicine, Zhejiang University · Anesthesia
Propofol is a rapid-acting intravenous sedative-hypnotic agent that enhances inhibitory GABA neurotransmission in the central nervous system.
Administering propofol · Iuliu Hatieganu University of Medicine and Pharmacy · Anesthesia
Propofol is a rapid-acting intravenous sedative-hypnotic agent that enhances inhibitory GABAergic neurotransmission in the central nervous system.
Sedation Propofol · RenJi Hospital · Anesthesia/Sedation
Propofol is a rapid-acting intravenous sedative-hypnotic that enhances inhibitory GABA neurotransmission in the central nervous system.
Propofol as induction agent · Fayoum University Hospital · Anesthesiology
Propofol is a rapid-acting intravenous sedative-hypnotic that enhances inhibitory GABA neurotransmission in the central nervous system to induce unconsciousness.

Phase 3 pipeline (1)

ICI35,868 (Diprivan) · AstraZeneca · Anesthesia
Propofol is a rapid-acting intravenous sedative-hypnotic agent that enhances inhibitory GABAergic neurotransmission in the central nervous system.

Patent intelligence

intravenous sedative hypnotic patent landscape — aggregated cliff calendar, attackable patents, originator estates