What are Intravenous iron replacement agent drugs?

Intravenous iron replacement agent drugs are pharmacologic agents that share a common mechanism (typically targeting Iron (Fe3+) for hemoglobin synthesis and erythropoiesis). 5 are currently marketed, with 2 more in clinical development.

What are the marketed Intravenous iron replacement agent drugs?

Marketed Intravenous iron replacement agent drugs include SFP, Iron Carboxymaltose, Ferric Carboxymaltose (FCM), intravenous iron carboxymaltose, Iron Sucrose (Venofer).

Intravenous iron replacement agent

5 marketed 2 in Phase 3

This page covers all Intravenous iron replacement agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Iron (Fe3+) for hemoglobin synthesis and erythropoiesis, Iron(III) ion; transferrin and ferritin (iron-binding proteins), Iron (Fe³⁺) delivery; transferrin and ferritin binding.

Targets

Iron (Fe3+) for hemoglobin synthesis and erythropoiesis · Iron(III) ion; transferrin and ferritin (iron-binding proteins) · Iron (Fe³⁺) delivery; transferrin and ferritin binding · Iron (Fe³⁺) delivery system; transferrin receptor-mediated uptake · Iron (Fe3+) delivery system · Iron (Fe3+) delivery via transferrin-mediated uptake

Marketed (5)

SFP · Rockwell Medical Technologies, Inc. · Hematology / Nephrology
SFP is an iron-based intravenous therapy that replenishes iron stores and stimulates erythropoiesis in patients with iron deficiency anemia.
Iron Carboxymaltose · Albina Nowak, MD · Hematology
Iron carboxymaltose delivers iron directly into the bloodstream as a stable iron-carbohydrate complex that is taken up by iron-binding proteins to replenish depleted iron stores.
Ferric Carboxymaltose (FCM) · American Regent, Inc. · Hematology
Ferric carboxymaltose delivers iron directly into the bloodstream as a stable iron-carbohydrate complex that is taken up by iron-binding proteins to replenish depleted iron stores.
intravenous iron carboxymaltose · University of Zurich · Hematology
Iron carboxymaltose is a ferric iron complex that delivers iron directly into the bloodstream to replenish depleted iron stores and restore hemoglobin production.
Iron Sucrose (Venofer) · American Regent, Inc. · Hematology
Iron sucrose delivers iron directly into the bloodstream as a stable complex to replenish iron stores and treat iron deficiency anemia.

Phase 3 pipeline (2)

IK-3001 · Mallinckrodt · Hematology
IK-3001 is an intravenous iron replacement therapy that replenishes depleted iron stores in patients with iron deficiency.
FCM · AMAG Pharmaceuticals, Inc. · Hematology
FCM (ferric carboxymaltose) delivers iron directly into the bloodstream to replenish iron stores and treat iron deficiency anemia.