Hedgehog pathway inhibitor — Patent Landscape

Aggregated US Orange Book patent estate across every drug in the hedgehog pathway inhibitor class. 12 active patents protecting 2 drugs. First major cliff: 2028. Daily refresh.

2
Drugs in class
12
Active US patents
46/100
Avg vulnerability
$150M
Annual revenue covered

Originators

Pfizer 10 patents Roche 2 patents

Cliff calendar — next 15 years

4
28
2
29
6
36

Drugs ranked by patent estate

Drug Originator Active patents Avg vuln Revenue First cliff
Daurismo
Glasdegib Maleate
 Pfizer 10 43 $150M 2028-06-29
Erivedge
vismodegib
 Roche 2 49 — 2028-11-11

Most attackable patents

Patent Drug Type Vuln Expiry
9278961 Erivedge method of use 75 2028-12-15
11891372 Daurismo method of use 75 2036-04-13
11891372 Daurismo method of use 75 2036-04-13
11168066 Daurismo method of use 62 2036-04-13
11168066 Daurismo method of use 62 2036-04-13
8431597 Daurismo formulation 55 2028-06-29
8431597 Daurismo formulation 55 2028-06-29
7888364 Erivedge composition of matter 22 2028-11-11
8148401 Daurismo composition of matter 17 2029-04-14
8148401 Daurismo composition of matter 17 2029-04-14

Strongest defences

Patent Drug Type Vuln Expiry
10414748 Daurismo composition of matter 4 2036-04-13
10414748 Daurismo composition of matter 4 2036-04-13
8148401 Daurismo composition of matter 17 2029-04-14
8148401 Daurismo composition of matter 17 2029-04-14
7888364 Erivedge composition of matter 22 2028-11-11
8431597 Daurismo formulation 55 2028-06-29
8431597 Daurismo formulation 55 2028-06-29
11168066 Daurismo method of use 62 2036-04-13
11168066 Daurismo method of use 62 2036-04-13
11891372 Daurismo method of use 75 2036-04-13

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