Glucosylceramide synthase inhibitor

This page covers all Glucosylceramide synthase inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glucosylceramide synthase, Glucosylceramide synthase (GCS).

Targets

Glucosylceramide synthase · Glucosylceramide synthase (GCS)

Marketed (1)

• Miglustat (Zavesca) · University of Washington · Rare genetic/lysosomal storage diseases
  Miglustat inhibits glucosylceramide synthase, reducing the accumulation of glucosylceramide and related glycosphingolipids in cells.

Phase 3 pipeline (1)

• Eliglustat GZ385660 · Sanofi · Rare/Genetic Disorders
  Eliglustat is a glucosylceramide synthase (GCS) inhibitor that reduces the production of glucosylceramide, a lipid that accumulates in Gaucher disease.