What are Glucagon receptor agonist drugs?

Glucagon receptor agonist drugs are pharmacologic agents that share a common mechanism (typically targeting Glucagon receptor (GCGR)). 2 are currently marketed, with 8 more in clinical development.

What are the marketed Glucagon receptor agonist drugs?

Marketed Glucagon receptor agonist drugs include Low-Dose Glucagon, Glucagon 12.5ng/kg/min.

Glucagon receptor agonist

2 marketed 6 in Phase 3 2 in Phase 2

This page covers all Glucagon receptor agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glucagon receptor (GCGR), GCGR (glucagon receptor), Glucagon receptor.

Targets

Glucagon receptor (GCGR) · GCGR (glucagon receptor) · Glucagon receptor

Marketed (2)

Low-Dose Glucagon · Steno Diabetes Center Copenhagen · Diabetes
Low-dose glucagon activates glucagon receptors to stimulate hepatic glucose output and counteract hypoglycemia in diabetes patients.
Glucagon 12.5ng/kg/min · Cambridge University Hospitals NHS Foundation Trust · Endocrinology
Glucagon binds to glucagon receptors on hepatic and other cells to stimulate glycogenolysis and gluconeogenesis, rapidly raising blood glucose levels.

Phase 3 pipeline (6)

Glucagon Hydrochloride Solution · Eli Lilly and Company · Endocrinology
Glucagon binds to glucagon receptors on hepatic cells to stimulate glycogenolysis and gluconeogenesis, rapidly raising blood glucose levels.
Intramuscular Glucagon · Eli Lilly and Company · Endocrinology / Diabetes
Glucagon binds to glucagon receptors on hepatic cells to stimulate glycogenolysis and gluconeogenesis, rapidly raising blood glucose levels.
Nasal Glucagon (NG) · Eli Lilly and Company · Endocrinology
Nasal glucagon activates glucagon receptors to rapidly increase blood glucose levels in hypoglycemic emergencies.
GlucaGen® HypoKit® · Adocia · Endocrinology / Diabetes
GlucaGen HypoKit is a glucagon formulation designed to rapidly raise blood glucose levels in patients experiencing severe hypoglycemia.
Glucagon Nasal Powder · Eli Lilly and Company · Endocrinology
Glucagon binds to glucagon receptors on hepatic cells to stimulate glycogenolysis and gluconeogenesis, rapidly raising blood glucose levels.
Glucagon IM · Eli Lilly and Company · Endocrinology
Glucagon binds to glucagon receptors on hepatic cells to stimulate glycogenolysis and gluconeogenesis, rapidly raising blood glucose levels.

Phase 2 pipeline (2)

CELSIOR® group · Hospices Civils de Lyon · Diabetes
CELSEOR is a glucagon receptor agonist.
AP1189 · SynAct Pharma Aps · Diabetes
AP1189 is a glucagon receptor agonist.