DPP-4 inhibitor combined with biguanide

This page covers all DPP-4 inhibitor combined with biguanide drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DPP-4 enzyme; metformin acts on multiple targets including mitochondrial complex I.

Targets

DPP-4 enzyme; metformin acts on multiple targets including mitochondrial complex I

Marketed (1)

• Sitagliptin combined with metformin · Sun Yat-sen University · Diabetes
  Sitagliptin inhibits DPP-4 to increase incretin levels and insulin secretion, while metformin reduces hepatic glucose production and improves insulin sensitivity.

Patent intelligence

• dpp 4 inhibitor combined with biguanide patent landscape — aggregated cliff calendar, attackable patents, originator estates