Inhalation Diagnostic Agent

This page covers all Inhalation Diagnostic Agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Sodium-dependent dopamine transporter, Amyloid beta A4 protein, somatostatin receptors, particularly SSTR2.

Targets

Sodium-dependent dopamine transporter · Amyloid beta A4 protein · somatostatin receptors, particularly SSTR2 · Glutamate carboxypeptidase 2 · High affinity choline transporter 1 · Estrogen receptor · glucose transporter proteins, hexokinase, glucose-6-phosphatase · Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial, Methionine synthase, Methionine synthase reductase · PSMA · Dopamine transporter (DaT)

Marketed (37)

• Xe 127 · Respiratory
• Datscan · Ge Hlthcare Inc · Neuroscience
  Datscan binds to dopamine transporters in the brain, allowing for imaging of dopamine activity.
• Lymphoseek Kit · Navidea Biopharms · Oncology
• Amyvid · Avid Radiopharms Inc · Neuroscience
  Amyvid works by binding to amyloid beta A4 protein in the brain, allowing for visualization of amyloid plaques in Alzheimer's disease.
• Detectnet · Radiomedix · Oncology
  Copper Cu 64 dotatate binds to somatostatin receptors, particularly SSTR2, on neuroendocrine tumor cells, allowing PET imaging.
• Xe 133 · Mallinckrodt · Respiratory
• Tc 99m filtered sulfur colloid · Memorial Health University Medical Center · Diagnostic Imaging
  Tc-99m filtered sulfur colloid is a radiopharmaceutical that accumulates in the reticuloendothelial system, allowing visualization of organs and tissues via gamma imaging.
• Ceretec · GE HealthCare · Other
• Myoview · GE HealthCare · Cardiovascular
  Myoview works by accumulating in the heart muscle and emitting gamma rays that are detected by a scanner, allowing for visualization of blood flow.
• Neuraceq · Life Molecular · Neuroscience
• Axumin · Blue Earth Diagnostics Ltd · Oncology
  Axumin works by binding to specific sites in the body, emitting positrons that create images during PET scans.
• Adreview · GE HealthCare · Oncology
  Adreview works by binding to specific cells or tissues in the body, allowing for imaging and diagnosis.
• AMMONIA N 13 · Other
• ammonia · Immunology
• Vizamyl · Ge Healthcare · Immunology
  Vizamyl works by binding to amyloid plaques in the brain, allowing for visualization through positron emission tomography (PET) imaging.
• Posluma · Blue Earth · Oncology
  Posluma works by binding to glutamate carboxypeptidase 2, a protein found in certain types of cancer cells.
• Tc-99m Pentetate · NYU Langone Health · Diagnostic Imaging / Nuclear Medicine
  Tc-99m Pentetate is a radiopharmaceutical that binds to transferrin in the blood and is filtered by the kidneys, allowing visualization of renal function and urinary tract anatomy via nuclear imaging.
• Choline C-11 · Mcprf · Oncology
  Choline C-11 works by binding to a specific target in the body, allowing for diagnostic imaging.
• Technetium Tc 99M Sestamibi · Cyclomedica · Oncology
  Technetium Tc 99m Sestamibi accumulates in viable myocardial tissue similar to thallous chloride TI-201, with possible mitochondrial retention.
• Amyvid · Avid Radiopharms Inc · Immunology
  Amyvid binds to beta-amyloid plaques in the brain, allowing for visualization of these plaques through PET imaging.
• Fludeoxyglucose F-18 · 3D Imaging Drug · Oncology
  Fludeoxyglucose F-18 is a radioactive molecule that accumulates in areas of high metabolic activity, allowing for imaging of various conditions.
• Choletec · Bracco · Urology
• Sestamibi · Lantheus Medical Imaging · Other
• Cerianna · GE HealthCare · Other
  Cerianna works by binding to estrogen receptors in the body, allowing for imaging of these receptors through positron emission tomography.
• Neuraceq · Piramal Imaging · Neuroscience
• XENON XE 133
• FLUDEOXYGLUCOSE F 18
  Fludeoxyglucose F-18 is a glucose analog that accumulates in cells with high glucose metabolism, reflecting metabolic activity.
• Ethylenediamine dihydrochloride allergen patch · Allerderm · Dermatology / Allergy & Immunology
  Ethylenediamine dihydrochloride serves as a contact allergen in patch testing to diagnose delayed-type hypersensitivity reactions and allergic contact dermatitis.
• Fludeoxyglucose F-18 · Downstate Clincl · Oncology
  Fludeoxyglucose F-18 is a radioactive sugar molecule that accumulates in cells with high metabolic activity, allowing for visualization of cancer and other conditions.
• FLURPIRIDAZ F 18
• Cyanocobalamin Co 57 · Mallinckrodt · Hematology
• TECHNETIUM TC-99M
  Technetium Tc 99m Sestamibi accumulates in viable myocardial tissue, similar to thallous chloride TI-201, for scintigraphic imaging.
• PIFLUFOLASTAT
  Piflufolastat F 18 binds to PSMA-expressing cells, including prostate cancer cells, and emits positrons for imaging.
• Vizamyl · GE HealthCare · Immunology
  Vizamyl works by binding to amyloid beta A4 protein in the brain, allowing for visualization of amyloid deposits in PET imaging.
• Flyrcado · Ge Hlthcare · Cardiovascular
  Flyrcado emits radiation to create detailed images of the heart, allowing for the diagnosis of coronary artery disease and other heart conditions.
• Posluma · Blue Earth · Oncology
  Posluma works by emitting radiation that helps doctors visualize and diagnose prostate cancer.
• Ioflupane I 123 · Ge Hlthcare Inc · Neuroscience
  Ioflupane I-123 binds to the dopamine transporter (DaT) in the striatum, allowing visualization of brain striata through SPECT imaging.

Phase 3 pipeline (4)

• Technetium99 · Milton S. Hershey Medical Center · Diagnostic Imaging / Nuclear Medicine
  Technetium-99m is a radioactive tracer that emits gamma radiation, allowing visualization of specific tissues and organs through nuclear imaging.
• PET MPI · GE Healthcare · Cardiovascular
  PET MPI is a myocardial perfusion imaging agent that uses a radioactive tracer to visualize blood flow to the heart muscle during stress and rest conditions.
• Iobenguane I -123 Injection · GE Healthcare · Oncology
  Iobenguane I-123 is a radiolabeled norepinephrine analog that accumulates in neuroendocrine tumors and the sympathetic nervous system, allowing for diagnostic imaging via single-photon emission computed tomography (SPECT).
• 13C-Methacetin · University of Texas Southwestern Medical Center · Hepatology / Gastroenterology
  13C-Methacetin is a stable isotope-labeled tracer used to assess hepatic metabolic function and liver synthetic capacity.

Patent intelligence

• diagnostic agent patent landscape — aggregated cliff calendar, attackable patents, originator estates