Coagulation factor concentrate

This page covers all Coagulation factor concentrate drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Factor VIII and von Willebrand Factor, Fibrinogen (Factor I), Clotting factors II, VII, IX, X (vitamin K-dependent factors).

Targets

Factor VIII and von Willebrand Factor · Fibrinogen (Factor I) · Clotting factors II, VII, IX, X (vitamin K-dependent factors) · Coagulation Factor XIII (F13A1)

Marketed (3)

• Plasma-derived FVIII/VWF concentrate · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Hematology
  This plasma-derived concentrate replaces deficient Factor VIII (FVIII) and von Willebrand Factor (VWF) to restore blood clotting ability in patients with hemophilia A or von Willebrand disease.
• Fibrinogen Concentrate Human · IRCCS Policlinico S. Donato · Hematology
  Fibrinogen Concentrate Human replaces or supplements deficient fibrinogen to restore normal blood clotting function.
• Prothrombin Complex Concentrate, Human · SHI Jia · Hematology / Hemostasis
  Prothrombin Complex Concentrate replaces deficient vitamin K-dependent clotting factors (II, VII, IX, X) to restore coagulation cascade function and reverse anticoagulation.

Phase 3 pipeline (1)

• FXIII Concentrate (Human) · CSL Behring · Hematology
  FXIII Concentrate replaces deficient coagulation Factor XIII to restore normal blood clot cross-linking and stabilization.