Ileal Bile Acid Transporter Inhibitor

This page covers all Ileal Bile Acid Transporter Inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Ileal sodium/bile acid cotransporter, IBAT (ileal bile acid transporter; SLC10A2).

Targets

Ileal sodium/bile acid cotransporter · IBAT (ileal bile acid transporter; SLC10A2)

Marketed (2)

• Livmarli · Mirum Pharma Inc · Hematology
  Livmarli works by blocking the ileal sodium/bile acid cotransporter, which reduces the amount of bile acids reabsorbed into the bloodstream.
• Bylvay · Ipsen · Infectious Disease
  Bylvay works by blocking the ileal sodium/bile acid cotransporter, a protein that helps reabsorb bile acids in the intestines.

Phase 3 pipeline (1)

• A4250 (odevixibat) · Albireo · Hepatology / Gastroenterology
  Odevixibat inhibits the ileal bile acid transporter (IBAT) to reduce bile acid reabsorption and increase fecal excretion, thereby lowering serum bile acids.

Patent intelligence

• bile acid transporter inhibitor patent landscape — aggregated cliff calendar, attackable patents, originator estates