Bile acid receptor agonist

This page covers all Bile acid receptor agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting FXR (farnesoid X receptor), TGR5.

Targets

FXR (farnesoid X receptor), TGR5

Marketed (1)

• Oral chenodeoxycholic acid stimulation · Lars Kristian Munck · Hepatology / Gastroenterology
  Chenodeoxycholic acid is a bile acid that activates farnesoid X receptor (FXR) and TGR5 signaling pathways to regulate bile acid metabolism and reduce cholestasis.

Phase 3 pipeline (1)

• CDCA Weight-Based Dose TID · Mirum Pharmaceuticals, Inc. · Hepatology / Gastroenterology
  CDCA (chenodeoxycholic acid) is a bile acid that activates farnesoid X receptor (FXR) and TGR5 signaling to reduce bile acid synthesis and improve cholestasis.

Patent intelligence

• bile acid receptor agonist patent landscape — aggregated cliff calendar, attackable patents, originator estates