Bile acid

This page covers all Bile acid drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Farnesoid X receptor (FXR), TGR5 receptor, Farnesoid X receptor (FXR), TGR5.

Targets

Farnesoid X receptor (FXR), TGR5 receptor · Farnesoid X receptor (FXR), TGR5

Marketed (2)

• Ursodeoxycholic acid · University of Oxford · Hepatology/Gastroenterology
  Ursodeoxycholic acid is a bile acid that reduces cholesterol saturation in bile and increases bile flow to improve hepatic function and reduce cholestasis.
• Ursodeoxycholic Acid (URSO) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Hepatology / Gastroenterology
  Ursodeoxycholic acid is a bile acid that reduces cholesterol saturation in bile and promotes its solubilization, while also exerting cytoprotective and anti-inflammatory effects on hepatocytes and biliary epithelium.

Phase 3 pipeline (2)

• Placebo Combined With Ursodeoxycholic Acid · Xijing Hospital of Digestive Diseases · Gastroenterology
  Ursodeoxycholic acid increases bile flow and reduces cholesterol saturation in bile to prevent gallstone formation and improve biliary function.
• Ursodeoxycholic Acid Capsules · Beijing Friendship Hospital · Hepatology / Gastroenterology
  Ursodeoxycholic acid is a bile acid that reduces cholesterol saturation in bile and increases bile flow to improve hepatic function and reduce cholestasis.