Barbiturate

This page covers all Barbiturate drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting GABA-A receptor alpha-1/beta-3/gamma-2, GABA-A receptor, GABA transaminase.

Targets

GABA-A receptor alpha-1/beta-3/gamma-2 · GABA-A receptor · GABA transaminase

Marketed (3)

• Brevital Sodium · Ph Health · Metabolic
• pentothal sodium · Ajou University School of Medicine · Anesthesia, Neurology
  Pentothal sodium is a barbiturate that enhances inhibitory neurotransmission by potentiating GABA receptors in the central nervous system, leading to sedation, anesthesia, and anticonvulsant effects.
• Phenobarbital Sodium Injection · PharPoint Research, Inc. · Neurology
  Phenobarbital sodium is a barbiturate that enhances inhibitory GABA neurotransmission in the central nervous system, producing sedative, hypnotic, and anticonvulsant effects.

Phase 3 pipeline (1)

• intramuscular paraldehyde · Kamuzu University of Health Sciences · Psychiatry
  Paraldehyde is a sedative and anticonvulsant that acts by inhibiting the activity of GABA transaminase, leading to increased levels of GABA in the brain.